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Coordinators of the Network
Adrian Goldman / tel. +358 9 191 58923 / adrian.goldman (at) helsinki.fi
Institute of Biotechnology, University of Helsinki
Macromolecular Structures Group - Institute of Biotechnology
Rik Wierenga / tel. +358 8 553 1199 / rik.wierenga (at) oulu.fi
Biocenter Oulu, University of Oulu
Protein Crystallography Core Facility - Biocenter Oulu
Structural biology and biophysics covers a wide range of topics, from protein production via structure determinations to biocomputational analysis. The Finnish national network comprises four major disciplines, all focused on experimental determination of macromolecular structures and elucidation of mechanisms by various time-resolved techniques. They are X-ray crystallography, nuclear magnetic resonance (NMR) spectroscopy, other time-resolved biophysical techniques, and electron microscopy. This network also benefits from central resources, such as CSC – IT Center for Science Ltd.) and from the Bioinformatics network. Four of the biocentres have macromolecular x-ray crystallography facilities (Institute of Biotechnology, BioCity Turku, Biocenter Oulu, Biocenter Kuopio), while the Institute of Biotechnology has a significant investment in nuclear magnetic resonance (NMR) spectroscopy, cryo-electron microscopy and novel three-dimensional methods and time-resolved optical spectroscopy (TROS). The National Biological NMR Centre at the Institute of Biotechnology provides state-of-the-art NMR instrumentation, methodology and expertise.
- Protein Crystallography Core Facility, Rik Wierenga
BioCity Turku / Turku Centre for Biotechnology
- Protein Crystallography Core Facility, Tassos Papageorgiou
Institute of Biotechnology
- Protein Crystallisation Facility, Adrian Goldman
- Biocenter Kuopio Facility, Juha Rouvinen
Institute of Biotechnology
- Finnish Biological NMR Center, Perttu Permi
- High-resolution mass spectrometry facility, Juha Rouvinen
See Biological Imaging network / Electron microscopy
Institute of Biomedical Technology
- Protein Production Service (BV / E.coli), Juha Määttä, Pirkko Heikinheimo
Helsinki Haartman Institute Protein Production Service
- Ritvos Lab (CHO, HEK), Olli Ritvos
No upcoming events.
Course contents include: cross-technology structural data integration methods, computational modelling and protein design, macromolecular complex production, electron tomography and correlative imaging techniques, biomolecular interactions, hybrid approaches in structural biology.
EMBO practical course on Modern Biophysical Methods for protein-ligand interactions,
October 17-21, 2011, Department of Biochemistry, University of Oulu, Oulu, Finland.