Latest News Biocenter Finland News

Oct 9, 2014

Rectors of the BF host Universities have appointed Professor emeritus Olli...

Jun 19, 2014

BF Annual Report 2013 has now been published. The report summarizes the activities of the...

Jun 9, 2014

17.9. 24.11.  

Structural biology

 

Coordinator of the Network

Rik Wierenga / tel. +358 8 553 1199 / rik.wierenga (at) oulu.fi

Biocenter Oulu, University of Oulu

Protein Crystallography Core Facility - Biocenter Oulu

 

Structural biology and biophysics covers a wide range of topics, from protein production via structure determinations to biocomputational analysis. The Finnish national network comprises four major disciplines, all focused on experimental determination of macromolecular structures and elucidation of mechanisms by various time-resolved techniques. They are X-ray crystallography, nuclear magnetic resonance (NMR) spectroscopy, other time-resolved biophysical techniques, and electron microscopy. This network also benefits from central resources, such as CSC – IT Center for Science Ltd.) and from the Bioinformatics network. Four of the biocentres have macromolecular x-ray crystallography facilities (Institute of Biotechnology, BioCity Turku, Biocenter Oulu, Biocenter Kuopio), while the Institute of Biotechnology has a significant investment in nuclear magnetic resonance (NMR) spectroscopy, cryo-electron microscopy and novel three-dimensional methods and time-resolved optical spectroscopy (TROS). The National Biological NMR Centre at the Institute of Biotechnology provides state-of-the-art NMR instrumentation, methodology and expertise.

 

Technology platform services

X-ray

Biocenter Oulu
- Protein Crystallography Core Facility, Rik Wierenga

 

BioCity Turku / Turku Centre for Biotechnology
- Protein Crystallography Core Facility, Tassos Papageorgiou

see also Bioinformatics: BioCity Turku/Åbo Akademi Structural bioinformatics laboratory

 

Institute of Biotechnology
- Protein Crystallisation Facility, Tommi Kajander

 

Biocenter Kuopio

- Biocenter Kuopio Facility, Juha Rouvinen

 

NMR & MS

Institute of Biotechnology
- Finnish Biological NMR Center, Hideo Iwai

Biocenter Kuopio
- High-resolution mass spectrometry facility, Juha Rouvinen

 

Electron microscopy

See Biological Imaging network / Electron microscopy

 

Protein production for biophysical and structural characterization

Institute of Biomedical Technology

- Protein Production Service (BV / E.coli), Juha Määttä

Helsinki Haartman Institute Protein Production Service

- Ritvos Lab (CHO, HEK), Olli Ritvos


 

Events Biocenter Finland Events

No upcoming events.

Other upcoming events

PDBe training by EMBL-EBI specialists

10-11th of June 2014, Helsinki University

You have a unique opportunity to learn how to use Protein Data Bank Tools from specialists coming from Hinxton, Cambridge.

Program and registration (by June 4th)

 

Instruct Training Courses

Course contents include: cross-technology structural data integration methods, computational modelling and protein design, macromolecular complex production, electron tomography and correlative imaging techniques, biomolecular interactions, hybrid approaches in structural biology.

 

Past events

Structural biology in science and medicine - BFSB Roadshows in Turku, Helsinki (Meilahti, Viikki), Tampere and Oulu in October-December 2011.

 

EMBO practical course on Modern Biophysical Methods for protein-ligand interactions,
October 17-21, 2011, Department of Biochemistry, University of Oulu, Oulu, Finland.
(http://events.embo.org/11-biophysical-methods/)