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Coordinator of the Network
Seppo Ylä-Herttuala / tel. +358 40 355 2075 / seppo.ylaherttuala(at)uef.fi
Biocenter Kuopio, University of Eastern Finland
The A. I. Virtanen Institute, Molecular Medicine Research Group
National Virus Vector Laboratory
Gene transfer techniques are an important tool in studies of gene function as well as in the clinical evaluation of new treatments. In research the most important impact of efficient transient and stable gene transfer methods is the generation of new cell lines or animal models for the basic research of protein functions. Many of these methods are based on utilization of viruses as means to target and deliver genes into appropriate cells. Alternatively, recent advances in the RNAi-methodology enable the same delivery method to be used to efficiently silence specific genes in cells. Successful work with these sophisticated viral methods requires special expertise and strict safety considerations both of which are found at all of the biocentres in Finland. In particular, the AIV Institute, specializing in gene transfer methods for drug development, has a long-standing experience with strict regulations and requirements essential for gene therapy based approaches for human patients. Some of their products are already in clinical trials. The AIV Institute is responsible for co-ordinating the development and production of gene transfer vectors at national level in Finland.
- Virus Vector Core Facility, Aki Manninen
BioCity Turku / Turku Centre for Biotechnology
- Viral Vector Facility, Eleanor Coffey
- Virus Vector Facility, Eric Dufour
Live and still virus imaging services
- Jyväskylä Environmental and Nanoscience Center, University of Jyväskylä, Maija Vihinen-Ranta
LentiGEMM-Kuopio, Kari Airenne
LentiGEMM-Turku, Jukka Westermarck, Mikko Laukkanen