Genome editing


Finnish genome editing center (FinGEEC) is a new infrastructure initiative to facilitate capture and development of novel genome editing technologies to generate knockout and sequence- specific gene expression control systems in cell lines, patient-derived cells and tissue models, and in ES cells/fertilized oocytes for rapid generation of genetically engineered rodents. FinGEEC is a timely initiative following current trend to move from unstable RNAi-based approaches to more stable genome editing. FinGEEC will integrate, provide support and spread the use of genome editing activities across Finnish biocenters. FinGEEC captures the latest genome editing technologies and via establishment of better infrastructures and services lowers the bar for research groups to access new disruptive technology in genetic analysis.


Contacts

Platform coordinator
Juha Klefström, Ph.D, Research Director, Research Programs Unit, University of Helsinki

Platform partners
Jukka Westermarck, M.D/Ph.D, Prof. & Johanna Ivaska, Ph.D, Academy Professor, Centre for Biotechnology, University of Turku and Åbo Akademi University, 
Pipsa Saharinen, Ph.D, Wihuri group leader & Biocentrum Helsinki, 
Emmy Verschuren, Ph.D, FIMM international group leader, FIMM, 
Petri Mäkinen, PhD, A.I. Virtanen Institute for Molecular Sciences, University of Eastern Finland.

Coordination with in vitro approaches and Biocenter Finland infrastructure networks:
Timo Otonkoski, M.D Ph.D. Professor of Medical Stem Cell Research, Research Programs Unit, University of Helsinki.

Coordination with in vivo approaches and Biocenter Finland infrastructure networks:
Model Organisms (Raija Soininen, Biocenter Oulu), Tissue Engineered Disease Models/TEDM (Jukka Westermarck, Biocenter Turku)

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